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Bishop Loughlin Memorial High School is a co-educational, college-preparatory, Roman Catholic high school located at 357 Clermont Avenue in the Ft. Greene neighborhood of Brooklyn, New York.

The school serves students in grades 9 through 12. Loughlin was founded in 1851 and was the first high school in the Diocese (1853), but today is run independently by the Christian Brothers in the Lasallian educational tradition, which holds central the appreciation of each student's uniqueness. Today, the school graduates at least 99% of its senior students with at least 97% of graduates matriculating to college each year. In 2023, Loughlin enrolls nearly 600 students, making it the fifth-largest Catholic high school in Brooklyn and Queens.